Topical 5‐fluorouracil as an adjunct treatment in equine corneolimbal squamous cell carcinoma
نویسندگان
چکیده
Summary An 11‐year‐old crossbreed mare was presented with a nodular, pink mass at the temporal corneolimbal junction of right eye. Histopathology confirmed diagnosis invasive squamous cell carcinoma. The underwent lamellar keratectomy and conjunctivectomy under general anaesthesia, followed by adjunctive topical chemotherapy 1% 5‐fluorouracil solution for 10 days post‐operatively. Adverse effects included moderate conjunctival inflammation exuberant granulation tissue formation surgical site, responding to debulking corticosteroid application. No regrowth present 12 months following discharge. This report describes successful use 5‐FU as an treatment equine ocular
منابع مشابه
Squamous cell carcinoma antigen as an adjunct tumour marker in primary carcinoma of the lung.
AIMS To determine (1) the detection rate of primary carcinoma of the lung by serological assay of CEA (carcinoembryonic antigen); and (2) whether addition of seroassay of squamous cell carcinoma related antigen before treatment improves detection sensitivity. METHODS A prospective study spanning 27 months was conducted at the University Hospital, Kuala Lumpur. Serum CEA (Abbott IMx) and serum...
متن کاملSuccessful treatment of invasive squamous cell carcinoma using topical imiquimod.
A 65-year-old man with a history of renal transplantation, chronic renal insufficiency after graft failure, and hemodialysis presented with a red palpable lesion on his right temple that had developed over a 3-year period (Figure 1A). The 4 3-cm erythematous hyperkeratotic plaque was located at the hair rim. On palpation, some induration and several papules were noted. Histologic examination of...
متن کاملTreatment of conjunctival squamous cell carcinoma with topical 5-fluorouracil.
AIM To evaluate the efficacy of topical 5-fluorouracil (5-FU) alone, without concurrent surgery or radiotherapy, for the treatment of conjunctival squamous cell carcinoma. METHODS Eight patients affected by conjunctival squamous cell carcinoma (three recurrent cases, three incompletely excised, and two untreated cases) were treated with 1% 5-FU eye drops. Topical 1% 5-FU was administered four...
متن کاملBasaloid Squamous Cell Carcinoma: An Unusual Ball-Valve Laryngeal Obstruction
Introduction: A rare case of basaloid squamous cell carcinoma (BSCC) of the larynx, which has not been previously reported, is described. Case Report: A 60-year-old man was presented to the Otolaryngology Department with progressive dyspnoea and dysphagia to solids for over a period of 1 week. Direct laryngoscopy revealed a tumour at the laryngeal aspect of the epiglottis, which prolapsed into...
متن کاملThe Cancer Stem Cell Hypothesis in Oral Squamous Cell Carcinoma: A New Target for the Treatment
Within a single tumor clone, cells have significantly different abilities to proliferate and form new tumors. This has led to the hypothesis that most cells in a cancer have a limited ability to divide and only a small subset of distinct cells, the cancer stem cells (CSCs), has the capacity to self-renew and form new tumors . It has been proposed that the development of tumors is based exclusiv...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Equine Veterinary Education
سال: 2021
ISSN: ['0957-7734', '2042-3292']
DOI: https://doi.org/10.1111/eve.13568